By binding to the adaptor protein SKP1 and serving as substrate receptors for the SKP1 Cullin. F-box E3 ubiquitin ligase complex. F-box proteins regulate critical cellular processes including cell cycle progression and membrane trafficking. While F-box proteins are conserved throughout eukaryotes and are well studied in yeast. https://www.hollandscountryclothinges.shop/product-category/quilted-bodywarmers/